Higher rates of coronary heart disease in African Americans might have more to do with the burden of risk factors than race, researchers reported here at the American Heart Association annual scientific sessions.
Age-adjusted and region-adjusted hazard ratios for fatal coronary heart disease was near 2 per 100 person-years for both white men and black men and white women and black women and became statistically nonsignificant after multivariable adjustment, according to Monika Safford, MD, of the University of Alabama at Birmingham, and colleagues.
Before adjusting for the burden of cardiovascular risk factors, it appeared that black men and women had a greater risk of disease, Safford and her team noted in a paper published simultaneously online in the Journal of the American Medical Association.
They enrolled 24,443 participants who were free of heart disease at the start of their prospective cohort study, Reasons for Geographic and Racial Differences in Stroke (REGARDS), between 2003 and 2007 and followed them through 2009.
During that time, there were 659 fatal and nonfatal coronary heart disease events including 153 in black men and 254 in white men, for an age-standardized incidence rate of 9 per 1,000 person-years (95% CI 7.5 to 10.8) in black men compared with 8.1 per 1,000 person-years (95% CI 6.9 to 9.4) for white men.
Fatal events occurred at a rate of 4 per 1,000 person years in blacks (95% CI 2.9 to 5.3) and a rate of 1.9 per 1,000 person-years for whites (95% CI 1.4 to 2.6).
06/11/2012 : By Ed Susman / MedPage Today.
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