Google Analytics

Wednesday, 31 October 2012

Canadian Scientists Say They've Discovered the Cause of High Cholesterol



Image : The Times Of India

High levels of so-called bad, or low-density lipoprotein (LDL) cholesterol — which so many of us are trying to control with statin pharmaceuticals — are enabled by a component of fat tissue, Canadian researchers have discovered.

A substance secreted by fat tissue called resistin increases the bad cholesterol, or LDL, in our liver cells. The liver is less able to clear "bad" cholesterol from the body. Resistin speeds up LDL accumulating in our arteries, increasing the risk of heart disease.

To make matters worse, resistin adversely impacts the effects of statins, the main cholesterol-reducing drug used in the treatment and prevention of cardiovascular disease. A staggering 40 per cent of people taking statins are resistant to their impact on lowering blood LDL, researchers say.

"The bigger implication of our results is that high blood resistin levels may be the cause of the inability of statins to lower patients' LDL cholesterol," said Shirya Rashid, MD, senior author of the study and assistant professor in the department of medicine at McMaster University in Ontario, Canada.

Dr. Rashid said the discovery could lead to revolutionary new therapeutic drugs, especially those that target and inhibit resistin and thereby increase the effectiveness of statins.

31/10/2012  :  Kathleen Struck / Everyday Health.

0 comments:

Post a Comment

My Blog List

Bloggers.com

Neeraj - Find me on Bloggers.com

468x60 Ads

Remove this add
THIS IS FEATURED POST 1 TITLE

THIS IS FEATURED POST 1 TITLE

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam

Quas molestias excepturi
THIS IS FEATURED POST 2 TITLE

THIS IS FEATURED POST 2 TITLE

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam

Impedit quo minus id
THIS IS FEATURED POST 3 TITLE

THIS IS FEATURED POST 3 TITLE

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam

Voluptates repudiandae kon
THIS IS FEATURED POST 4 TITLE

THIS IS FEATURED POST 4 TITLE

Lorem ipsum dolor sit amet, consectetur adipisicing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam

Mauris euismod rhoncus tortor

Blog links

Bloggers.com

Neeraj - Find me on Bloggers.com

Follow Us

Google+ Badge

Followers

Search

 
Blogger Widgets