Women who underwent breast radiotherapy did not have a higher risk of long-term cardiac morbidity compared with patients who had modified radical mastectomy.
Point out that cardiac interventions (coronary artery bypass graft or percutaneous coronary intervention) occurred in similar numbers of patients who had radiotherapy compared with modified radical mastectomy.
Women who underwent breast radiotherapy did not have a higher risk of long-term cardiac morbidity than patients who had modified radical mastectomy, according to a quarter century's worth of data.
Nearly 250 stage I-II breast cancer patients treated from 1979-1987 in an NCI trial were randomized to breast-conserving therapy (BCT) or modified radical mastectomy, and of those, 102 women were alive at 25.7 years (P=0.38), reported Charles Simone II, MD, from the University of Pennsylvania in Philadelphia.
"Over the past two decades, radiation therapy has become more precise and safer with modern techniques," Simone, told attendees an American Society for Radiation Oncology meeting press conference. "We are pleased to find that early-stage breast cancer patients treated with modern radiation therapy treatment planning techniques do not have an increased risk of long-term cardiac toxicity and that BCT with radiation should remain a standard treatment option."
31/10/2012 : By Ed Susman / MedPage Today.
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